Unveiling the impact of community knowledge in malaria programmes: A scoping review protocol
This scoping review promises an in-depth understanding of current research regarding the impact of community knowledge in malaria programmes. The identification of knowledge gaps and intervention needs serves as a valuable resource for malaria-affected countries. The profound implications of community knowledge underscore its pivotal role in enhancing the effectiveness of prevention, control, and elimination efforts. […]
Plasmodium gametocyte carriage in humans and sporozoite rate in anopheline mosquitoes in Gondar zuria district, Northwest Ethiopia
Although the overall burden of malaria is decreasing in Ethiopia, a recent report of an unpredictable increased incidence may be related to the presence of community-wide gametocyte-carrier individuals and a high proportion of infected vectors. This study aimed to reveal the current prevalence of gametocyte-carriage and the sporozoite infectivity rate of Anopheles vectors for Plasmodium parasites. Minwuyelet, A., Abiye, […]
Coordinated molecular and ecological adaptations underlie a highly successful parasitoid
The success of an organism depends on the molecular and ecological adaptations that promote its beneficial fitness. Parasitoids are valuable biocontrol agents for successfully managing agricultural pests, and they have evolved diversified strategies to adapt to both the physiological condition of hosts and the competition of other parasitoids. Pang, L., Fang, G., Liu, Z., Dong, […]
Driving evolution in wild plants
Two groups of scientists independently engineer gene drives in Arabidopsis thaliana, demonstrating the possibility for spreading fitness-reducing genetic modifications through wild populations of plants for population suppression. Imagine a future where yield-robbing agricultural weeds or biodiversity threatening invasive plants could be kept on a genetic leash, or where the evolutionary rescue of extinction-threatened plant species […]
Comparative analysis of Wolbachia maternal transmission and localization in host ovaries
Many insects and other animals carry microbial endosymbionts that influence their reproduction and fitness. These relationships only persist if endosymbionts are reliably transmitted from one host generation to the next. Wolbachia are maternally transmitted endosymbionts found in most insect species, but transmission rates can vary across environments. Maternal transmission of wMel Wolbachia depends on temperature […]
The impact of Plasmodium-driven immunoregulatory networks on immunity to malaria
Malaria, caused by infection with Plasmodium parasites, drives multiple regulatory responses across the immune landscape. These regulatory responses help to protect against inflammatory disease but may in some situations hamper the acquisition of adaptive immune responses that clear parasites. In addition, the regulatory responses that occur during Plasmodium infection may negatively affect malaria vaccine efficacy […]