The boundary problem: Defining and delineating the community in field trials with gene drive organisms
Background
Despite widespread and worldwide efforts to eradicate vector-borne diseases such as malaria, these diseases continue to have an enormous negative impact on public health. For this reason, scientists are working on novel control strategies, such as gene drive technologies (GDTs). As GDT research advances, researchers are contemplating the potential next step of conducting field trials. An important point of discussion regarding these field trials relates to who should be informed, consulted, and involved in decision-making about their design and launch.
de Graeff, N., Pirson, I., van der Graaf, R., Bredenoord, A. L., & Jongsma, K. R. (2023). The boundary problem: Defining and delineating the community in field trials with gene drive organisms. Bioethics.