Publications

Analysis and control of Aedes Aegypti mosquitoes using sterile-insect techniques with Wolbachia

May 24, 2023

Background Combining Sterile and Incompatible Insect techniques can significantly reduce mosquito populations and prevent the transmission of diseases between insects and humans. This paper describes impulsive differential equations for the control of a mosquito with Wolbachia. Several interesting conditions are created when sterile male mosquitoes are released impulsively, ensuring both open- and closed-loop control. To […]

Gene drive mosquitoes can aid malaria elimination by retarding Plasmodium sporogonic development

May 24, 2023

Background Gene drives hold promise for the genetic control of malaria vectors. The development of vector population modification strategies hinges on the availability of effector mechanisms impeding parasite development in transgenic mosquitoes. We augmented a midgut gene of the malaria mosquito Anopheles gambiae to secrete two exogenous antimicrobial peptides, magainin 2 and melittin. This small genetic modification, […]

A detailed landscape of CRISPR-Cas-mediated plant disease and pest management

May 24, 2023

Background Genome editing technology has rapidly evolved to knock-out genes, create targeted genetic variation, install precise insertion/deletion and single nucleotide changes, and perform large-scale alteration. The flexible and multipurpose editing technologies have started playing a substantial role in the field of plant disease management. CRISPR-Cas has reduced many limitations of earlier technologies and emerged as […]

Advances in Mosquito Control: A Comprehensive Review

May 24, 2023

Background Mosquitoes are the important global vectors transmitting diseases of human concern such as dengue, Chikungunya, Malaria, encephalitis and yellow fever, etc. Management of mosquito-borne diseases largely relies on the vector management because of the lack of effective medication and vaccination. Several strategies have been formulated and applied in the fields to control mosquitoes; yet […]

Applications of gene drive systems for population suppression of insect pests

May 24, 2023

Background Population suppression is an effective way for controlling insect pests and disease vectors, which cause significant damage to crop and spread contagious diseases to plants, animals and humans. Gene drive systems provide innovative opportunities for the insect pests population suppression by driving genes that impart fitness costs on populations of pests or disease vectors. […]