Publications

Climate change and malaria control: a call to urgent action from Africa’s frontlines

June 11, 2025

In December 2024, L’Initiative-Expertise France organized a workshop in Musanze, Rwanda, for National Malaria Control and Elimination Programmes (NMC/EPs) representatives from 19 sub-Saharan African countries. The workshop focused on surveillance, modeling, climate forecasting, and innovative control methods to mitigate climate change impacts on malaria. Participants shared challenges, experiences and best practices. Key challenges highlighted include […]

The fast-evolving FIKK kinase family of Plasmodium falciparum can be inhibited by a single compound

May 23, 2025

Of 250 Plasmodium species, 6 infect humans, with P. falciparum causing over 95% of 600,000 annual malaria-related deaths. Its pathology arises from host cell remodelling driven by over 400 exported parasite proteins, including the FIKK kinase family. About one million years ago, a bird-infecting Plasmodium species crossed into great apes and a single non-exported FIKK kinase gained an export element. This led […]

Suppression of Aedes mosquito populations with the boosted sterile insect technique in tropical and Mediterranean urban areas

May 23, 2025

Aedes mosquitoes are the vectors of dengue viruses and other arboviruses, which threaten billions of people all over the world. The boosted sterile insect technique (boosted SIT) is a version of SIT in which irradiated sterile males also transmit a biocide to immature stages. Bouyer, J., Gil, D.A., Mora, I.P. et al. Suppression of Aedes mosquito populations with the […]

Prevalence of Anopheles stephensi in Horn of Africa: a systematic review and meta-analysis

May 6, 2025

Anopheles stephensi has been a primary cause of malaria spread in urban areas. The World Health Organization announced a threat alert in 2019 that highlighted the An. stephensi outbreak in the Horn of Africa. Currently, there is insufficient information on the prevalence of An. stephensi. Therefore, this systematic review and meta-analysis aimed to determine the pooled prevalence of An. stephensi in […]

The CABIM3, enriched space for the improvement of fruit flies used in the sterile insect technique, first approaches

April 28, 2025

The High Biosecurity House of the Mediterranean Fly in Metapa (CABIM3, in its Spanish acronym) is a space within the new Moscamed Mexico facility designed to select favorable traits that mitigate the negative effects of mass production while enhancing male competitiveness, ultimately increasing the efficiency of the sterile insect technique (SIT). The CABIM3 serves as […]